1. Signaling Pathways
  2. Anti-infection
  3. Influenza Virus

Influenza Virus

Influenza virus belongs to the Orthomyxoviridae group, which are enveloped, segmented, single-stranded negative sense RNA viruses. The group includes three types of influenza viruses, A, B and C. Type B and C viruses only infect humans, but the type A viruses infect humans, horses, swine, other mammals, and a wide variety of domesticated and wild birds. Human influenza A and B viruses cause seasonal epidemics of disease almost every winter in the United States. The emergence of a new and very different influenza virus to infect people can cause an influenza pandemic. Influenza type C infections cause a mild respiratory illness and are not thought to cause epidemics. Each virus subtype has mutated into a variety of strains with differing pathogenic profiles; some are pathogenic to one species but not others, some are pathogenic to multiple species.

Influenza Virus 相关产品 (33):

Cat. No. Product Name Effect Purity
  • HY-13318
    Oseltamivir acid Inhibitor 98.60%
    Oseltamivir acid,是GS 4071的乙酯前药,是流感病毒神经氨酸酶的抑制剂,IC50 约为100 nM。
  • HY-P0017
    Aprotinin Inhibitor
    Aprotinin是分离自牛肺的丝氨酸蛋白酶 (BPTI) 抑制剂,对胰蛋白酶胰凝乳蛋白酶胰凝乳蛋白酶的 Ki 值分别为0.06 pM和9 nM。
  • HY-109025A
    Baloxavir Inhibitor 99.71%
    Baloxavir 是一种抗流感病毒药物,来自专利 WO 2017104691 A1。
  • HY-101950
    KIN1148 Inhibitor >98.0%
    KIN1148是一种小分子 IRF3 激动剂,用作增强流感疫苗效率的佐剂。
  • HY-12353A
    Pimodivir Inhibitor 99.04%
    Pimodivir (VX-787) 是一种可口服的甲型流感病毒聚合酶抑制剂,通过抑制PB2亚基起作用。
  • HY-111802
    3,4'-Dihydroxyflavone Inhibitor 98.20%
    3,4'-Dihydroxyflavone (3,4'-DHF) 是一种具有口服活性的黄酮类化合物,具有抗病毒活性,如,甲型流感病毒 (Influenza A virus)
  • HY-122907
    JNJ4796 Inhibitor
    JNJ4796 是具有口服活性的流感病毒融合性抑制剂,通过抑制血球凝集素 (HA) 介导的融合来中和甲型流感病毒。JNJ4796 和广泛中和抗体 (bnAbs) 的功能类似。
  • HY-14818
    Laninamivir Inhibitor
    Laninamivir (R 125489) 是一种有效的流感神经氨酸酶 (NA) 抑制剂,其对流感病毒 H12N5 NA (N5),pH1N1 N1 NA (p09N1) 和 A/RI/5+/1957 H2N2 N2 (p57N2) 的 IC50 分别为 0.90 nM、1.83 nM 和 3.12 nM。
  • HY-17016
    Oseltamivir phosphate Inhibitor 99.85%
    Oseltamivir phosphate (GS 4104) 是一种神经氨酸酶 (neuraminidase) 抑制剂,用于预防和治疗流感 (influenza AB)。
  • HY-B0217
    Nitazoxanide Inhibitor
    Nitazoxanide是抗原生动物化合物,对犬流感病毒的IC50为0.17 到 0.21μM。
  • HY-13210
    Zanamivir Inhibitor 99.59%
    Zanamivir是流感病毒的神经氨酸酶抑制剂,对于流感病毒A和B的IC50值分别为0.95 nM和2.7 nM。
  • HY-14904A
    Arbidol hydrochloride Inhibitor 99.44%
    Arbidol (Umifenovir)盐酸盐是广谱的抗病毒化合物,能通过阻断病毒与宿主细胞的融合抑制包装病毒进入细胞。
  • HY-N0243
    Theaflavin Inhibitor 99.09%
    Theaflavin 是一种天然的甲型流感 (H1N1) 神经氨酸酶抑制剂。
  • HY-50001
    Nucleozin Inhibitor 99.45%
    Nucleozin靶向流感A的核蛋白(NP)。
  • HY-107902
    RIG-1 modulator 1 Inhibitor 98.81%
    RIG-1 modulator 1 是一种抗病毒化合物,可以用来治疗病毒性感染包括流感病毒,HBV, HCVHIV 来自专利 WO 2015172099 A1。
  • HY-B0402A
    Amantadine hydrochloride Inhibitor >98.00%
    Amantadine盐酸盐是抗流感病毒和抗帕金森病化合物。
  • HY-17015
    Peramivir trihydrate Inhibitor 99.91%
    Peramivir (RWJ 270201; Rapiacta; BCX 1812)是高活性的流感病毒神经氨酸苷酶抑制剂,IC50的中位值为0.09 nM。
  • HY-W015346
    Desaminotyrosine Inhibitor 99.32%
    Desaminotyrosine 是一种微生物相关的代谢物,通过扩大 I 型干扰素 (type I interferon) 信号来阻止 influenza 的发生。
  • HY-U00160
    SP187 Inhibitor 99.30%
    SP187 是一种靶向作用于宿主的针对丝状病毒感染的亚胺糖。SP187 在体内抗流感和登革热。
  • HY-B0338A
    Rimantadine hydrochloride Inhibitor >98.0%
    Rimantadine(Flumadine)盐酸盐是口服抗流感病毒A化合物。
Isoform Specific Products

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