1. Signaling Pathways
  2. Protein Tyrosine Kinase/RTK
  3. BMX Kinase

BMX Kinase

Bmx is a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Bmx is characterized by an N-terminal pleckstrin homology domain and has been shown to be a downstream effector of phosphatidylinositol 3-kinase. P21-activated kinase 1 (Pak1), another well characterized effector of phosphatidylinositol 3-kinase, has been implicated in the progression of breast cancer cells.

BMX Kinase 相关产品 (2):

Cat. No. Product Name Effect Purity
  • HY-80002
    BMX-IN-1 Inhibitor 98.88%
    BMX-IN-1是BMX 激酶IC50 值为8.0 nM。
  • HY-101267
    CHMFL-BMX-078 Inhibitor >98.0%
    CHMFL-BMX-078是高效的,选择性的,不可逆的,类型II BMX激酶抑制剂,IC50值为11 nM。
Isoform Specific Products

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

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