1. Signaling Pathways
  2. Metabolic Enzyme/Protease
  3. 5 alpha Reductase

5 alpha Reductase

5 alpha Reductase (5α-reductases), also known as 3-oxo-5α-steroid 4-dehydrogenases, are enzymes involved in steroid metabolism。 They participate in 3 metabolic pathways: bile acid biosynthesis, androgen and estrogen metabolism, and prostate cancer。

5 alpha Reductase 相关产品 (6):

Cat. No. Product Name Effect Purity
  • HY-13635
    Finasteride Inhibitor 99.96%
    Finasteride是口服活性的睾酮5α-还原酶抑制剂,Ki为10 nM。
  • HY-13613
    Dutasteride Inhibitor 99.79%
    Dutasteride (GG745)是5α还原酶同工酶抑制剂,还可能因其结构域DHT相似对雄激素受体(AR)产生脱靶效应。
  • HY-107385
    Epristeride Inhibitor 99.96%
    Epristeride 是一种新型的 5α-还原酶 (5α-reductase) 抑制剂。
  • HY-B0141A
    Alpha-Estradiol Inhibitor 99.46%
    Alpha-Estradiol 是一种雌性激素,同时为 5α-reductase 抑制剂,用于局部药物治疗雄原性脱发。
  • HY-13635A
    Finasteride acetate Inhibitor
    Finasteride醋酸盐是口服活性的睾酮5α-还原酶抑制剂。
  • HY-U00125
    CGP-53153 Inhibitor
    CGP-53153是甾体类的 5 alpha reductase 抑制剂,在大鼠和人前列腺组织中的 IC50 值分别为36 nM。
Isoform Specific Products

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